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There are 16 twelve-letter words containing A, 3E, O, P, S and T

DECOMPENSATEdecompensate v. (Medicine, psychology, of a bodily organ or mental state) To deteriorate in function due to an inability…
DECOMPENSATE v. to fail to compensate.
DEUTERANOPESdeuteranopes n. Plural of deuteranope.
DEUTERANOPE n. an individual affected with deuteranopia, red-green colour-blindness.
ESPAGNOLETTEespagnolette n. A locking device normally mounted on a pair French windows or casement window.
ESPAGNOLETTE n. (French) the fastening of a French window.
EXOPEPTIDASEexopeptidase n. (Biochemistry) Any of a group of enzymes which catalyze the removal of a single amino acid from the…
EXOPEPTIDASE n. any of a group of enzymes that hydrolyze peptide bonds.
EXPECTORATESexpectorates v. Third-person singular simple present indicative form of expectorate.
EXPECTORATE v. to eject from the throat or lungs by coughing or hawking and spitting.
OBSTREPERATEobstreperate v. To make a loud noise.
OBSTREPERATE v. (Sterne) to make an unruly noise.
OBTEMPERATESobtemperates v. Third-person singular simple present indicative form of obtemperate.
OBTEMPERATE v. to obey (a judgment or decree), also OBTEMPER.
OVEROPERATESoveroperates v. Third-person singular simple present indicative form of overoperate.
OVEROPERATE v. to operate to excess.
PATHOGENESESpathogeneses n. Plural of pathogenesis.
PATHOGENESIS n. the production and development of disease, also PATHOGENY.
PERSEVERATORperseverator n. One who perseverates.
PERSEVERATOR n. one who perseverates.
POETASTERIESpoetasteries n. Plural of poetastery.
POETASTERY n. the writing of inferior verse, also POETASTRY.
SPELAEOTHEMSSPELAEOTHEM n. a term for depositional features, such as stalactites and stalagmites, found in caves, also SPELEOTHEM.
SPERMATOCELEspermatocele n. A retention cyst of a tubule of the rete testis or the head of the epididymis distended with barely…
SPERMATOCELE n. a cystic swelling of the testicle arising from the epididymis and containing sperm.
STEAROPTENESstearoptenes n. Plural of stearoptene.
STEAROPTENE n. the part of an essential oil that separates out as a solid on cooling or standing.
SUPEREROGATEsupererogate adj. (Rare) Supererogatory.
supererogate v. (Intransitive, theology, Catholicism) To do more than God commands.
supererogate v. (Intransitive, obsolete, with for) To make up with excess for the lack prepositioned by for.
TRADESPEOPLEtradespeople n. Plural of tradesperson.
TRADESPEOPLE n. people engaged in trade.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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