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There are 6 fifteen-letter words containing A, 2D, E, M, 2N and S

ANDROMEDOTOXINSandromedotoxins n. Plural of andromedotoxin.
ANDROMEDOTOXIN n. a poisonous substance extracted from plants of the heath family and used in medicine to lower high blood pressure.
DEMANDINGNESSESDEMANDINGNESS n. the state of being demanding.
DIMENHYDRINATESdimenhydrinates n. Plural of dimenhydrinate.
DIMENHYDRINATE n. a crystalline antihistamine used esp. to prevent nausea, as in motion sickness.
DISCOMMENDATIONdiscommendation n. (Archaic) blame; censure; reproach; shunning.
DISCOMMENDATION n. the act of discommending.
MADDENINGNESSESMADDENINGNESS n. the state of being maddening.
UNDEMANDINGNESSundemandingness n. The quality of being undemanding; lack of difficulty or challenge.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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See this list for:

  • English Wiktionary: 75 words
  • Scrabble in French: 14 words
  • Scrabble in Spanish: 55 words
  • Scrabble in Italian: 6 words
  • Scrabble in German: no word
  • Scrabble in Romanian: 3 words


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