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There are 20 twelve-letter words containing A, D, E, I, 2O and 2S

AECIDOSPORESAECIDOSPORE n. a spore produced in an aecidium, also AECIOSPORE.
APOTHEOSISEDapotheosised v. Simple past tense and past participle of apotheosise.
APOTHEOSISE v. to bring to perfection, also APOTHEOSIZE.
ASTRONOMISEDastronomised v. Simple past tense and past participle of astronomise.
ASTRONOMISE v. to study astronomy, also ASTRONOMIZE.
BASIDIOSPOREbasidiospore n. (Biology) A sexually reproductive spore produced by fungi of the phylum Basidiomycota.
BASIDIOSPORE n. a spore produced by a basidium.
COMPASSIONEDcompassioned v. Simple past tense and past participle of compassion.
COMPASSION v. (archaic) to pity.
CONSOLIDATESconsolidates v. Third-person singular simple present indicative form of consolidate.
CONSOLIDATE v. to join together into one whole.
DISCONSOLATEdisconsolate adj. Cheerless, dreary.
disconsolate adj. Seemingly beyond consolation; inconsolable.
disconsolate n. (Obsolete) Disconsolateness.
ENDORSATIONSendorsations n. Plural of endorsation.
ENDORSATION n. approval or support, also INDORSATION.
FOOLHARDISESFOOLHARDISE n. (Spenser) foolhardiness, also FOOLHARDIZE.
ICOSAHEDRONSicosahedrons n. Plural of icosahedron.
ICOSAHEDRON n. a polyhedron having 20 faces.
KETOACIDOSESketoacidoses n. Plural of ketoacidosis.
KETOACIDOSIS n. a condition in which excessive levels of ketone bodies and glucose cause the blood to become acidic.
KETOACIDOSISketoacidosis n. (Biology, medicine) A severe form of ketosis, most commonly seen in diabetics, in which so much ketone…
KETOACIDOSIS n. a condition in which excessive levels of ketone bodies and glucose cause the blood to become acidic.
LOADSAMONIESLOADSAMONEY n. wealth accumulated as a result of the economic boom of the 1980s.
OUTPASSIONEDoutpassioned v. Simple past tense and past participle of outpassion.
OUTPASSION v. to exceed in passion.
PAEDOLOGISTSpaedologists n. Plural of paedologist.
pædologists n. Plural of pædologist.
PAEDOLOGIST n. one who studies the growth and development of children, also PEDOLOGIST.
PSEUDOLOGIASPSEUDOLOGIA n. lying in speech or writing.
RADIOSCOPIESradioscopies n. Plural of radioscopy.
RADIOSCOPY n. examination of opaque bodies by X-rays.
SCORPAENOIDSscorpaenoids n. Plural of scorpaenoid.
SCORPAENOID n. any member of the scorpion fish family.
SOMATOMEDINSsomatomedins n. Plural of somatomedin.
SOMATOMEDIN n. an endogenous peptide pronounced in the liver.
SPODOMANCIESSPODOMANCY n. divination by means of ashes.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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