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There are 16 words containing 3A, C, D, E and 2S

ACADEMICALISMSACADEMICALISM n. close adherence to formal academic teaching.
ASCLEPIADACEOUSasclepiadaceous adj. (Botany) Relating to the milkweeds.
ASCLEPIADACEOUS adj. belonging to the Asclepiadaceae, the milkweed and swallowwort family.
DECASUALISATIONDECASUALISATION n. the process of making employment not casual, also DECASUALIZATION.
DESACRALISATIONDESACRALISATION n. the act of desacralising, also DESACRALIZATION.
DISACCHARIDASEdisaccharidase n. (Biochemistry) Any of a class of glycoside hydrolases, enzymes that break down disaccharides into monosaccharides.
DISACCHARIDASE n. an enzyme (as maltase or lactase) that hydrolyzes disaccharides.
DISACCHARIDASESdisaccharidases n. Plural of disaccharidase.
DISACCHARIDASE n. an enzyme (as maltase or lactase) that hydrolyzes disaccharides.
DISAPPEARANCESdisappearances n. Plural of disappearance.
DISAPPEARANCE n. the act of disappearing.
DISCAPACITATESdiscapacitates v. Third-person singular simple present indicative form of discapacitate.
DISCAPACITATE v. to incapacitate.
GALACTOSIDASEgalactosidase n. (Biochemistry) Any of several enzymes that catalyze the hydrolysis of a galactoside.
GALACTOSIDASE n. an enzyme (as lactase) that hydrolyzes a galactoside.
GALACTOSIDASESgalactosidases n. Plural of galactosidase.
GALACTOSIDASE n. an enzyme (as lactase) that hydrolyzes a galactoside.
MACADAMISERSMACADAMISER n. one who macadamises, also MACADAMIZER.
MACADAMISESmacadamises v. Third-person singular simple present indicative form of macadamise.
MACADAMISE v. to cover a road with small broken stones, also MACADAMIZE.
PARADOXICALNESSparadoxicalness n. The state or quality of being paradoxical.
PARADOXICAL n. of the nature of a paradox, also PARADOXAL.
SCARABAEIDSscarabaeids n. Plural of scarabaeid.
scarabæids n. Plural of scarabæid.
SCARABAEID n. a beetle of the Scarabaeus genus of lamellicorn beetles, also SCARAB, SCARABEE, SCARABOID.
SCARABAEOIDSscarabaeoids n. Plural of scarabaeoid.
SCARABAEOID n. any of various kinds of lamellicorn beetle, esp. Scarabaeus sacer (sacred scarab), regarded by the ancient Egyptians as divine.
TRADESCANTIAStradescantias n. Plural of tradescantia.
TRADESCANTIA n. any plant of the American Tradescantia genus, with attractive, often variegated foliage, aka spiderwort.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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