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There are 19 twelve-letter words containing 2A, C, F, I, O, R and S

AFFRICATIONSaffrications n. Plural of affrication.
AFFRICATION n. the act of making a sound affricative.
FABRICATIONSfabrications n. Plural of fabrication.
FABRICATION n. the act of fabricating.
FACILITATORSfacilitators n. Plural of facilitator.
FACILITATOR n. one that facilitates.
FACTIONARIESfactionaries n. Plural of factionary.
FACTIONARY n. a member of a faction.
FIBROSARCOMAfibrosarcoma n. (Oncology) A fibroblastic sarcoma: a malignant tumor derived from fibrous connective tissue.
FIBROSARCOMA n. a sarcoma formed of spindle-shaped cells in collagenous fibrils.
FRACTIONATESfractionates v. Third-person singular simple present indicative form of fractionate.
FRACTIONATE v. to separate a mixture into different portions esp. by a fractional process.
FRACTOSTRATIFRACTOSTRATUS n. a type of cloud.
FRANCISATIONfrancisation n. Non-Oxford British spelling standard spelling of francization.
Francisation n. Non-Oxford British spelling standard spelling of francization.
FRANCISATION n. the act of making French, also FRANCIZATION.
FRANCOMANIASFRANCOMANIA n. an obsession with France and the French.
PACIFICATORSpacificators n. Plural of pacificator.
PACIFICATOR n. a peacemaker.
PARFOCALISEDPARFOCALISE v. to make parfocal, also PARFOCALIZE.
PARFOCALISESPARFOCALISE v. to make parfocal, also PARFOCALIZE.
PARFOCALIZESparfocalizes v. Third-person singular simple present indicative form of parfocalize.
PARFOCALIZE v. to make parfocal, also PARFOCALISE.
RAREFACTIONSrarefactions n. Plural of rarefaction.
RAREFACTION n. the act of rarefying.
SATISFACTORYsatisfactory adj. Done to satisfaction; adequate or sufficient.
satisfactory adj. Causing satisfaction; agreeable or pleasant; satisfying.
satisfactory adj. (Theology) Making atonement for a sin; expiatory.
SCARIFICATORscarificator n. (Surgery, archaic) An instrument, principally used in cupping, containing several lancets that are moved…
SCARIFICATOR n. a surgical instrument for scarifying, also SCARIFIER.
STALACTIFORMstalactiform adj. Resembling a stalactite.
STALACTIFORM adj. shaped like a stalactite or icicle.
SUBFACTORIALsubfactorial n. (Mathematics, combinatorics) The result of deranging a number. In equations, it is usually symbolised…
SUBFACTORIAL n. something below a factorial.
TRAFFICATORStrafficators n. Plural of trafficator.
TRAFFICATOR n. formerly, a movable pointer raised or lowered by the driver of a vehicle to warn of a change of direction.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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