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There are 12 words containing A, I, O, 2P and 2U

FLAVOPURPURINflavopurpurin n. (Organic chemistry) 1,2,6-trihydroxyanthraquinone.
FLAVOPURPURIN n. a yellow crystalline dye derived from anthraquinone.
FLAVOPURPURINSFLAVOPURPURIN n. a yellow crystalline dye derived from anthraquinone.
OUTPOPULATINGoutpopulating v. Present participle of outpopulate.
OUTPOPULATE v. to surpass in population.
PAPULIFEROUSpapuliferous adj. Pimply; covered with papulae.
PAPULIFEROUS adj. pimply.
PLEUROPNEUMONIApleuropneumonia n. (Pathology) inflammation of the pleura and lungs; a combination of pleurisy and pneumonia, especially…
PLEUROPNEUMONIA n. pneumonia aggravated by pleurisy.
PUPIPAROUSpupiparous adj. (Entomology) Producing young that are ready to pupate.
PUPIPAROUS adj. bearing, or containing, a pupa.
SUBPOPULATIONsubpopulation n. A subdivision of a population.
SUBPOPULATION n. an identifiable fraction or subdivision of a population.
SUBPOPULATIONSsubpopulations n. Plural of subpopulation.
SUBPOPULATION n. an identifiable fraction or subdivision of a population.
SUPPURATIONsuppuration n. (Medicine) Decay in tissue producing pus, or the pus itself.
suppuration n. (Medicine) The act of suppurating.
SUPPURATION n. the discharge of pus.
SUPPURATIONSsuppurations n. Plural of suppuration.
SUPPURATION n. the discharge of pus.
UNPOPULARITIESunpopularities n. Plural of unpopularity.
UNPOPULARITY n. the state of being unpopular.
UNPOPULARITYunpopularity n. The property or degree of being unpopular.
UNPOPULARITY n. the state of being unpopular.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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