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There are 20 words containing A, 2F, I, M and 2S

MASTIFFSmastiffs n. Plural of mastiff.
Mastiffs n. Plural of Mastiff.
MASTIFF n. a large shorthaired breed of dog.
CAFFEISMSCAFFEISM n. an addiction to caffeine.
DISAFFIRMSdisaffirms v. Third-person singular simple present indicative form of disaffirm.
DISAFFIRM v. to assert the contrary of; to contradict.
SUFFRAGISMsuffragism n. (Historical) A political movement in the late 19th century that fought for women’s right to vote in…
SUFFRAGISM n. voting rights.
CAFFEINISMSCAFFEINISM n. an unhealthy condition caused by taking too much caffeine.
FRAMESHIFTSframeshifts n. Plural of frameshift.
FRAMESHIFT n. a term in genetic manipulation, a type of mutation.
RUFFIANISMSruffianisms n. Plural of ruffianism.
RUFFIANISM n. being a ruffian.
SUFFRAGISMSSUFFRAGISM n. voting rights.
BULLMASTIFFSbullmastiffs n. Plural of bullmastiff.
Bullmastiffs n. Plural of Bullmastiff.
BULLMASTIFF n. a breed of dog.
OFFICIALISMSofficialisms n. Plural of officialism.
OFFICIALISM n. excessive devotion to routine or position.
SUFFUMIGATESsuffumigates v. Third-person singular simple present indicative form of suffumigate.
SUFFUMIGATE v. to fumigate from below.
SEMIOFFICIALSSorry, definition not available.
SUFFRAGETTISMsuffragettism n. The suffragette movement for women’s voting rights.
SUFFRAGETTISM n. belief in the aims of the suffragette.
DISAFFIRMANCESdisaffirmances n. Plural of disaffirmance.
DISAFFIRMANCE n. the act of disaffirming.
EFFEMINATENESSeffeminateness n. Effeminacy.
EFFEMINATENESS n. the state of being effeminate.
SUFFRAGETTISMSSUFFRAGETTISM n. belief in the aims of the suffragette.
SUFFUMIGATIONSsuffumigations n. Plural of suffumigation.
SUFFUMIGATION n. fumigation from below.
DISAFFIRMATIONSdisaffirmations n. Plural of disaffirmation.
DISAFFIRMATION n. the act of disaffirming.
DISAFFORESTMENTdisafforestment n. Disafforestation.
DISAFFORESTMENT n. the act of disafforesting.
FORISFAMILIATESforisfamiliates v. Third-person singular simple present indicative form of forisfamiliate.
FORISFAMILIATE v. (Scots) to emancipate from parental authority.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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