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There are 18 words containing A, C, D, 2S and 2U

CARDUUSESCARDUUS n. (Shakespeare) a thistle.
CAUCUSSEDcaucussed v. Simple past tense and past participle of caucus.
CAUCUS v. to hold a political meeting.
SUCCEDANEOUSsuccedaneous adj. Pertaining to, or acting as, a succedaneum; supplying the place of something else; being, or employed…
SUCCEDANEOUS adj. subrogated, substituted.
SUCCEDANEUMSsuccedaneums n. Plural of succedaneum.
SUCCEDANEUM n. (Latin) a substitute; a remedy.
AUDACIOUSNESSaudaciousness n. Risky or daring behaviour.
audaciousness n. Impudence.
AUDACIOUSNESS n. the state of being audacious.
AUTODESTRUCTSautodestructs v. Third-person singular simple present indicative form of autodestruct.
AUTODESTRUCT v. to self-destruct.
DOLICHOSAURUSDOLICHOSAURUS n. any member of the Dolichosauria, a group of Cretaceous fossil reptiles.
DRACUNCULUSESDRACUNCULUS n. the green dragon genus of Araceae.
PSEUDOCARPOUSPSEUDOCARPOUS adj. of or like a pseudocarp.
UNDERSURFACESundersurfaces n. Plural of undersurface.
UNDERSURFACE n. an underside.
UNDISCUSSABLEundiscussable adj. Not discussable; that cannot be discussed.
UNDISCUSSABLE adj. that cannot be discussed, also UNDISCUSSIBLE.
DRACUNCULIASESDRACUNCULIASIS n. a disease that is caused by infestation with the guinea worm and that has been eradicated in most regions except Africa.
DRACUNCULIASISdracunculiasis n. (Medicine) an infection caused by an infestation of the parasite Dracunculus medinensis.
DRACUNCULIASIS n. a disease that is caused by infestation with the guinea worm and that has been eradicated in most regions except Africa.
GLUCURONIDASESglucuronidases n. Plural of glucuronidase.
GLUCURONIDASE n. an enzyme that hydrolyzes a glucuronide.
STRUCTURALISEDstructuralised v. Simple past tense and past participle of structuralise.
STRUCTURALISE v. to organize or incorporate into a structure, also STRUCTURALIZE.
AUDACIOUSNESSESaudaciousnesses n. Plural of audaciousness.
AUDACIOUSNESS n. the state of being audacious.
DOLICHOSAURUSESDOLICHOSAURUS n. any member of the Dolichosauria, a group of Cretaceous fossil reptiles.
SUPERABUNDANCESsuperabundances n. Plural of superabundance.
SUPERABUNDANCE n. extreme abundance.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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