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There are 18 words containing A, C, 2D, E, F and T

DEFECATEDdefecated v. Simple past tense and past participle of defecate.
DEFECATE v. to void excrement, also DEFAECATE.
DEFAECATEDdefaecated v. Simple past tense and past participle of defaecate.
defæcated v. Obsolete spelling of defecated; simple past tense and past participle of defæcate.
DEFAECATE v. to void excrement, also DEFECATE.
DEFALCATEDdefalcated v. Simple past tense and past participle of defalcate.
DEFALCATE v. to embezzle money held on trust.
DIFFRACTEDdiffracted v. Simple past tense and past participle of diffract.
DIFFRACT v. to separate into parts.
FECUNDATEDfecundated v. Simple past tense and past participle of fecundate.
FECUNDATE v. to make fruitful or prolific.
CODEFENDANTcodefendant n. (Law) Any of several defendants answering the same charge.
co-defendant n. Alternative spelling of codefendant.
CODEFENDANT n. a joint defendant.
DISAFFECTEDdisaffected v. Simple past tense and past participle of disaffect.
disaffected adj. Alienated or estranged, often with hostile effect; rebellious, resentful; disloyal.
disaffected adj. (Obsolete) Affected with disease.
HANDCRAFTEDhandcrafted adj. Made by hand or using the hands, as opposed to by mass production or using machinery.
HANDCRAFT v. to fashion by hand.
NIDIFICATEDnidificated v. Simple past tense and past participle of nidificate.
NIDIFICATE v. to construct a nest.
CODEFENDANTScodefendants n. Plural of codefendant.
co-defendants n. Plural of co-defendant.
CODEFENDANT n. a joint defendant.
CONFEDERATEDconfederated v. Simple past tense and past participle of confederate.
CONFEDERATE v. to unite in a confederacy.
DESANCTIFIEDdesanctified v. Simple past tense and past participle of desanctify.
DECAFFEINATEDdecaffeinated adj. From which caffeine has been removed (e.g. decaffeinated coffee).
DECAFFEINATE v. to remove caffeine from.
DEFLOCCULATEDdeflocculated v. Simple past tense and past participle of deflocculate.
DEFLOCCULATE v. to deprive of flocculation.
DISAFFECTEDLYdisaffectedly adv. In a disaffected manner.
DISAFFECTED adv. DISAFFECT, to take away the affection of; to make discontented or unfriendly.
UNCONFEDERATEDunconfederated adj. Not confederated.
UNCONFEDERATED adj. not confederated.
DEACIDIFICATIONdeacidification n. (Chemistry) The act or process of removing or neutralizing acid.
DEACIDIFICATION n. the act of deacidifying.
DISAFFECTEDNESSdisaffectedness n. The quality of being disaffected.
DISAFFECTEDNESS n. the state of being disaffected.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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