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There are 12 words containing 2A, 3E, O and P

ARCHAEOPTERYXESarchaeopteryxes n. Plural of archaeopteryx.
ARCHAEOPTERYX n. a Jurassic fossil bird of the Archaeopteryx genus, with a long bony tail, sharp-toothed jaws, and wings bearing three clawed digits.
BALNEOTHERAPIESbalneotherapies n. Plural of balneotherapy.
BALNEOTHERAPY n. treatment by natural waters.
HAEMATOPOIESESHAEMATOPOIESIS n. the formation of blood, also HAEMOPOIESIS, HEMATOPOIESIS, HEMOPOIESIS.
HEPATOMEGALIEShepatomegalies n. Plural of hepatomegaly.
HEPATOMEGALY n. enlargement of the liver.
HERPETOFAUNAEHERPETOFAUNA n. (Latin) snake life.
MEGAGAMETOPHYTEmegagametophyte n. (Biology) Any gametophyte that develops from a megaspore.
megagametophyte n. (Biology) A female gametophyte.
MEGAGAMETOPHYTE n. the gametophyte developing vegetatively from the megaspore of a heterosporous plant.
MEGALOCEPHALIESMEGALOCEPHALY n. the condition of having an unusually large head or cranial capacity, also MEGACEPHALY.
NEOARSPHENAMINEneoarsphenamine n. A derivative of arsphenamine once used to treat syphilis and yaws.
NEOARSPHENAMINE n. a derivative of arsenic used in treating syphilis.
OVEREXTRAPOLATESorry, definition not available.
PALAEOECOLOGIESpalaeoecologies n. Plural of palaeoecology.
PALAEOECOLOGY n. the study of early ecology.
PERGAMENTACEOUSpergamentaceous adj. (Biology, now chiefly botany) Reminiscent of parchment.
PERGAMENTACEOUS adj. parchment-like, also PERGAMENEOUS.
SPERMATOTHECAEspermatothecae n. Plural of spermatotheca.
SPERMATOTHECA n. a receptacle for storing sperm.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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