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There are 11 words containing 2A, D, F, O and 2T

AUTOGRAFTEDautografted v. Simple past tense and past participle of autograft.
AUTOGRAFT v. to make such a graft.
FRACTIONATEDfractionated v. Simple past tense and past participle of fractionate.
FRACTIONATE v. to separate a mixture into different portions esp. by a fractional process.
ANTIDEFAMATIONantidefamation adj. Opposing the defamation of a particular group. Chiefly in direct or oblique reference to the Anti-Defamation League.
ANTIDEFAMATION adj. designed to counter defamation.
UNFRACTIONATEDunfractionated adj. Not fractionated.
DEFRAGMENTATIONdefragmentation n. (Computing) The action of defragmenting, particularly with respect to a computer disk or drive.
DISAFFECTIONATEdisaffectionate adj. Not disposed to affection; unfriendly.
DISAFFECTIONATE adj. showing disaffection.
DISSATISFACTIONdissatisfaction n. Unhappiness or discontent.
dissatisfaction n. The cause of such feelings.
DISSATISFACTION n. the state of being dissatisfied.
DISSATISFACTORYdissatisfactory adj. Causing dissatisfaction.
DISSATISFACTORY adj. causing dissatisfaction.
STRAIGHTFORWARDstraightforward adj. Proceeding in a straight course or manner; not deviating.
straightforward adj. Easy, simple, uncomplicated, without difficulty.
straightforward adj. (Figurative) direct; forthright; frank; sincere.
TETRAHYDROFURANtetrahydrofuran n. (Organic chemistry) A heterocyclic ether having a five-membered ring with four carbon atoms and one…
TETRAHYDROFURAN n. a flammable liquid ether derived from furan and used as a solvent and as an intermediate in organic synthesis.
ULTRAFASTIDIOUSultrafastidious adj. Extremely fastidious.
ULTRAFASTIDIOUS adj. extremely fastidious.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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