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There are 7 words containing 2A, C, 2O and 2U

AQUIFOLIACEOUSaquifoliaceous adj. (Botany) Belonging to the Aquifoliaceae.
AQUIFOLIACEOUS adj. belonging to the holly family.
AUTOCEPHALOUSautocephalous adj. (Christianity, of a church) Fully independent of the authority of any other church.
autocephalous adj. (Christianity, of a bishop) Presiding over an autocephalous church.
autocephalous adj. (Comparable) Independent; self-directed.
AUTOINOCULATIONautoinoculation n. Inoculation into oneself (as of modified cells).
autoinoculation n. (Pathology) The spread of a disease to another part of the body via inoculation.
AUTOINOCULATION n. self-inoculation.
BIOACCUMULATIONbioaccumulation n. (Biology) The process by which substances accumulate in the tissues of living organisms; used especially…
BIOACCUMULATION n. accumulation in a biological system over time.
GLAUCOMATOUSglaucomatous adj. Having the nature of glaucoma.
GLAUCOMATOUS adj. affected by glaucoma.
PORTULACACEOUSportulacaceous adj. (Botany) Of or relating to the family Portulacaceae of plants including the spring beauty.
PORTULACACEOUS adj. belonging to the leek family.
SIMAROUBACEOUSsimaroubaceous adj. (Botany) Belonging to the family Simaroubaceae of tropical and subtropical trees.
SIMAROUBACEOUS adj. belonging to the Simarubaceae, a family of tropical trees related to the Rutaceae, also SIMARUBACEOUS.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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