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There are 14 words containing 2A, C, I, M, S and X

ALEXIPHARMICSalexipharmics n. Plural of alexipharmic.
ALEXIPHARMIC n. an antidote to poison.
ANTICLIMAXESanticlimaxes n. Plural of anticlimax.
anti-climaxes n. Plural of anti-climax.
ANTICLIMAX n. the usually sudden transition in discourse from a significant idea to a trivial or ludicrous idea.
AXINOMANCIESAXINOMANCY n. divination using an axe or hatchet.
AXIOMATICSaxiomatics n. The study of all the axioms associated with a particular subject.
AXIOMATICS n. the study of axioms and axiom systems.
AXISYMMETRICALaxisymmetrical adj. Axisymmetric.
AXISYMMETRICAL adj. symmetrical in respect to an axis, also AXISYMMETRIC.
AXOPLASMICaxoplasmic adj. Of or pertaining to axoplasm.
AXOPLASMIC adj. relating to axoplasm.
EXCLAMATIONSexclamations n. Plural of exclamation.
EXCLAMATION n. a sharp or sudden utterance.
EXCLAMATIVESEXCLAMATIVE n. a word or sentence that denotes an exclamation.
EXTRAMUSICALextramusical adj. Apart from and in addition to music.
EXTRAMUSICAL adj. lying outside the province of music.
HEXADECIMALShexadecimals n. Plural of hexadecimal.
HEXADECIMAL n. a number system with a base of 16.
MAXICOATSmaxicoats n. Plural of maxicoat.
MAXICOAT n. a long coat.
PLAGIOCLIMAXESplagioclimaxes n. Plural of plagioclimax.
PLAGIOCLIMAX n. the climax stage of a community, influenced by man or some other outside factor.
TOXICOMANIAStoxicomanias n. Plural of toxicomania.
TOXICOMANIA n. a morbid craving for poisons.
XANTHOCHROMIASXANTHOCHROMIA n. any yellowish discoloration, esp. of the cerebrospinal fluid.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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