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There are 10 words containing 3A, C, 2D and E

MACADAMEDmacadamed v. Simple past tense and past participle of macadam.
MACADAMED adj. paved with macadam.
CAVALCADEDcavalcaded v. Simple past tense and past participle of cavalcade.
CAVALCADE v. to ride in a cavalcade.
MACADAMISEDmacadamised v. Simple past tense and past participle of macadamise.
MACADAMISE v. to cover a road with small broken stones, also MACADAMIZE.
MACADAMIZEDmacadamized v. Simple past tense and past participle of macadamize.
MACADAMIZE v. to cover a road with small broken stones, also MACADAMISE.
UNMACADAMISEDunmacadamised adj. Alternative form of unmacadamized.
UNMACADAMISED adj. not macadamised, also UNMACADAMIZED.
UNMACADAMIZEDunmacadamized adj. Not macadamized.
UNMACADAMIZED adj. not macadamized, also UNMACADAMISED.
DISACCHARIDASEdisaccharidase n. (Biochemistry) Any of a class of glycoside hydrolases, enzymes that break down disaccharides into monosaccharides.
DISACCHARIDASE n. an enzyme (as maltase or lactase) that hydrolyzes disaccharides.
DISCAPACITATEDdiscapacitated v. Simple past tense and past participle of discapacitate.
DISCAPACITATE v. to incapacitate.
RADIOACTIVATEDradioactivated v. Simple past tense and past participle of radioactivate.
RADIOACTIVATE v. to activate by radio.
DISACCHARIDASESdisaccharidases n. Plural of disaccharidase.
DISACCHARIDASE n. an enzyme (as maltase or lactase) that hydrolyzes disaccharides.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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