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There are 17 words containing 4A, C, I and O

ACARIDOMATIAACARIDOMATIUM n. a habitat for mites provided by certain plants that benefit from their presence, also ACARODOMATIUM.
ACARODOMATIAacarodomatia n. Plural of acarodomatium.
ACARODOMATIUM n. a habitat for mites provided by certain plants that benefit from their presence, also ACARIDOMATIUM.
ACROAMATICALacroamatical adj. Synonym of acroamatic.
ACROAMATICAL adj. abstruse, esoteric, also ACROAMATIC.
APOCATASTASISapocatastasis n. (Rare) restoration, renovation, reestablishment, particularly…
APOCATASTASIS n. the state of being restored to a previous condition, esp. the final restitution of all things at the appearance of the Messiah.
GALACTOSAEMIAgalactosaemia n. Alternative spelling of galactosemia.
GALACTOSAEMIA n. the presence of galactose in the blood, also GALACTOSEMIA.
TOBACCANALIANtobaccanalian adj. (Rare) Relating to the smoking of tobacco.
tobaccanalian n. (Rare) A person who smokes tobacco.
TOBACCANALIAN n. (facetious) a smoker.
ANACARDIACEOUSanacardiaceous adj. (Botany) Of or relating to the family Anacardiaceae of cashews and sumacs.
ANACARDIACEOUS adj. belonging to the Anacardiaceae, the cashew-nut family.
ANGIOSARCOMATAangiosarcomata n. Plural of angiosarcoma.
ANGIOSARCOMA n. a malignant tumour of the vascular epithelia, occurring e.g. in the liver.
GALACTOSAEMIASgalactosaemias n. Plural of galactosaemia.
GALACTOSAEMIA n. the presence of galactose in the blood, also GALACTOSEMIA.
MACADAMISATIONmacadamisation n. Alternative form of macadamization.
MACADAMISATION n. the process of macadamising, also MACADAMIZATION.
MACADAMIZATIONmacadamization n. (Britain) The process of paving roads with macadam.
MACADAMIZATION n. the process of macadamizing, also MACADAMISATION.
MEGALOMANIACALmegalomaniacal adj. Megalomaniac.
MEGALOMANIACAL adj. relating to megalomania, also MEGALOMANIC.
TOBACCANALIANStobaccanalians n. Plural of tobaccanalian.
TOBACCANALIAN n. (facetious) a smoker.
MACADAMISATIONSMACADAMISATION n. the process of macadamising, also MACADAMIZATION.
MACADAMIZATIONSmacadamizations n. Plural of macadamization.
MACADAMIZATION n. the process of macadamizing, also MACADAMISATION.
PALAEOBOTANICALpalaeobotanical adj. Alternative spelling of paleobotanical.
PALAEOBOTANICAL adj. relating to palaeobotany, the study of fossil plants, also PALAEOBOTANIC.
PALAEOGRAPHICALpalaeographical adj. Of or pertaining to palaeography.
palæographical adj. Obsolete spelling of paleographical.
PALAEOGRAPHICAL adj. related to palaeography, the study of ancient writings, also PALEOGRAPHIC.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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