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There are 3 eight-letter words containing A, I, N, 2R and 2T

IRRITANTirritant adj. Causing irritation or inflammation.
irritant adj. (Law, Scotland) Rendering null and void; conditionally invalidating.
irritant n. Any medication designed to cause irritation.
NITRATORnitrator n. A reaction vessel in which nitration takes place.
nitrator n. A device for spreading nitrate fertilizer on the soil.
NITRATOR n. one that nitrates.
RETIRANTRETIRANT n. one who has retired from his vocation, also RETIREE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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