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There are 3 eight-letter words containing A, E, 2I, M and 2N

ANTIMINEantimine adj. (Military) Countering or opposing mines (explosive devices).
ANTIMINE adj. designed to counteract landmines.
INDAMINEindamine n. (Chemistry) any of a range of organic bases related to phenazine; they form indigo-coloured salts used in making dyes.
INDAMINE n. any unstable organic base whose salts are blue or green dyes, also INDAMIN.
MAINLINEmainline adj. Normal, principal or standard.
mainline adj. (Rail transport) Of or pertaining to the principal route or line of a railway.
mainline adj. (Rail transport) Of or pertaining to a surface railway as distinct from an underground, elevated or light rail one.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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