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There are 3 eight-letter words containing A, C, D, M, N and 2O

CODOMAINcodomain n. (Mathematics, mathematical analysis) The target set into which a function is formally defined to map…
CODOMAIN n. in mathematics, the range, the set of output values of a function (the domain is the set of inputs).
COMMANDOcommando n. A small fighting force specially trained for making quick destructive raids against enemy-held areas.
commando n. A commando trooper.
commando n. (Historical) An organized force of Boer troops in South Africa; a raid by such troops.
MONOACIDmonoacid n. (Chemistry) Any acid that has only one replaceable hydrogen ion.
MONOACID n. a compound having one hydrogen atom replaceable by a negative or acid atom or radical, also MONACID.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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