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There are 3 eight-letter words containing 2A, E, M, 2T and U

AMPUTATEamputate v. (Obsolete) To cut off, to prune.
amputate v. To surgically remove a part of the body, especially a limb.
AMPUTATE v. to cut off.
AUTOMATEautomate v. (Transitive, intransitive) To replace or enhance human labor with machines.
AUTOMATE v. to convert to automatic control.
MATURATEmaturate v. (Transitive) To bring to ripeness or maturity; to ripen.
maturate v. (Medicine, transitive) To promote the perfect suppuration of (an abscess).
maturate v. (Medicine, intransitive) To undergo perfect suppuration.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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