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There are 4 eight-letter words containing 2A, C, 2E, M and T

CASEMATEcasemate n. (Military) A bombproof chamber, usually of masonry, in which cannon may be placed, to be fired through…
casemate n. (Architecture) A hollow molding, chiefly in cornices.
CASEMATE n. a bombproof chamber or armoured compartment.
EMACIATEemaciate v. (Transitive) To make extremely thin or wasted.
emaciate v. (Intransitive) To become extremely thin or wasted.
emaciate adj. Emaciated.
MACERATEmacerate v. To soften (something) or separate it into pieces by soaking it in a heated or unheated liquid.
macerate v. (Archaic) To make lean; to cause to waste away.
macerate v. (Obsolete) To subdue the appetite by poor or scanty diet; to mortify.
RACEMATEracemate n. (Chemistry) a racemic mixture.
racemate n. (Chemistry) any salt or ester of racemic acid.
racemate n. One racing in the same race.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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