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There are 7 fourteen-letter words containing 4A, C, I and O

ANACARDIACEOUSanacardiaceous adj. (Botany) Of or relating to the family Anacardiaceae of cashews and sumacs.
ANACARDIACEOUS adj. belonging to the Anacardiaceae, the cashew-nut family.
ANGIOSARCOMATAangiosarcomata n. Plural of angiosarcoma.
ANGIOSARCOMA n. a malignant tumour of the vascular epithelia, occurring e.g. in the liver.
GALACTOSAEMIASgalactosaemias n. Plural of galactosaemia.
GALACTOSAEMIA n. the presence of galactose in the blood, also GALACTOSEMIA.
MACADAMISATIONmacadamisation n. Alternative form of macadamization.
MACADAMISATION n. the process of macadamising, also MACADAMIZATION.
MACADAMIZATIONmacadamization n. (Britain) The process of paving roads with macadam.
MACADAMIZATION n. the process of macadamizing, also MACADAMISATION.
MEGALOMANIACALmegalomaniacal adj. Megalomaniac.
MEGALOMANIACAL adj. relating to megalomania, also MEGALOMANIC.
TOBACCANALIANStobaccanalians n. Plural of tobaccanalian.
TOBACCANALIAN n. (facetious) a smoker.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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