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There are 20 twelve-letter words containing A, 2E, H, 2M and S

AMPHETAMINESamphetamines n. Plural of amphetamine.
AMPHETAMINE n. a synthetic, potentially habit-forming drug used as an appetite suppressant and in the treatment of narcolepsy.
HAEMACHROMESHAEMACHROME n. a blood pigment, such as haemoglobin, that carries oxygen, also HEMACHROME.
HAEMATEMESEShaematemeses n. Plural of haematemesis.
HAEMATEMESIS n. vomiting of blood from the stomach, also HEMATEMESIS.
HAEMATEMESIShaematemesis n. (British spelling) Alternative spelling of hematemesis.
hæmatemesis n. Obsolete form of hematemesis.
HAEMATEMESIS n. vomiting of blood from the stomach, also HEMATEMESIS.
HAEMOCHROMESHAEMOCHROME n. a blood pigment, such as haemoglobin, that carries oxygen, also HEMOCHROME.
HAMMERSTONEShammerstones n. Plural of hammerstone.
HAMMERSTONE n. a stone used as a hammer in the production of tools during the Acheulian period.
HECTOGRAMMEShectogrammes n. Plural of hectogramme.
HECTOGRAMME n. a measure of weight, containing a hundred grams, also HECTOGRAM, HEKTOGRAM.
IMPEACHMENTSimpeachments n. Plural of impeachment.
IMPEACHMENT n. the act of impeaching.
MATHEMATISEDmathematised v. Simple past tense and past participle of mathematise.
MATHEMATISE v. to make mathematical, also MATHEMATICISE, MATHEMATICIZE, MATHEMATIZE.
MATHEMATISESmathematises v. Third-person singular simple present indicative form of mathematise.
MATHEMATISE v. to make mathematical, also MATHEMATICISE, MATHEMATICIZE, MATHEMATIZE.
MATHEMATIZESmathematizes v. Third-person singular simple present indicative form of mathematize.
MATHEMATIZE v. to make mathematical, also MATHEMATICISE, MATHEMATICIZE, MATHEMATISE.
MESOTHELIOMAmesothelioma n. (Pathology, oncology) An uncommon malignant tumour of the mesothelium, usually of the lungs after exposure…
MESOTHELIOMA n. a tumour of the mesothelia.
METAMORPHOSEmetamorphose v. (Of a moth or insect, intransitive) To undergo metamorphosis.
metamorphose v. (By extension, intransitive) To undergo some transformation.
metamorphose v. (Transitive) To transform (something) so that it has a completely different appearance.
METHANAMIDESmethanamides n. Plural of methanamide.
METHANAMIDE n. an amide derived from formic acid, aka formamide.
METHENAMINESmethenamines n. Plural of methenamine.
METHENAMINE n. hexamethylenetetramine esp. when used in the form of an organic salt to treat urinary tract infections.
METHYLAMINESmethylamines n. Plural of methylamine.
METHYLAMINE n. an inflammable gas, obtainable from herring brine.
MISEMPHASISEmisemphasise v. Alternative form of misemphasize.
MISEMPHASISE v. to emphasise wrongly, also MISEMPHASIZE.
MISEMPHASIZEmisemphasize v. To emphasize incorrectly or inappropriately.
MISEMPHASIZE v. to emphasize wrongly, also MISEMPHASISE.
SLEDGEHAMMERsledgehammer n. A hammer that consists of a large, heavy, broad and flat block of metal (the head) attached to a handle…
sledgehammer v. To strike with a sledgehammer.
SLEDGEHAMMER n. a large hammer used e.g. for breaking rocks.
XERANTHEMUMSxeranthemums n. Plural of xeranthemum.
XERANTHEMUM n. any plant of the Xeranthemum genus of plants of southern Europe, belonging to the thistle family.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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