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There are 3 twelve-letter words containing A, C, 2I, M, T and X

ANTICLIMAXESanticlimaxes n. Plural of anticlimax.
anti-climaxes n. Plural of anti-climax.
ANTICLIMAX n. the usually sudden transition in discourse from a significant idea to a trivial or ludicrous idea.
AXISYMMETRICaxisymmetric adj. Exhibiting symmetry around an axis; exhibiting cylindrical symmetry.
axi-symmetric adj. Alternative form of axisymmetric.
AXISYMMETRIC adj. symmetrical in respect to an axis, also AXISYMMETRICAL.
TOXICOMANIAStoxicomanias n. Plural of toxicomania.
TOXICOMANIA n. a morbid craving for poisons.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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