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There are 13 twelve-letter words containing A, C, F, 2N, O and U

BIFUNCTIONALbifunctional adj. Having two functions.
bifunctional adj. (Chemistry, of a compound) Having two functional groups or binding sites.
bifunctional adj. (Chemistry, of a reaction) Involving two functional groups or binding sites.
CONFOUNDABLEconfoundable adj. That can be confounded.
CONFOUNDABLE adj. capable of being confounded.
CONFUTATIONSconfutations n. Plural of confutation.
CONFUTATION n. the act of confuting.
DIFUNCTIONALdifunctional adj. Bifunctional.
DIFUNCTIONAL n. a compound with two highly reactive sites in each molecule.
FECUNDATIONSfecundations n. Plural of fecundation.
FECUNDATION n. the act of making fecund.
FUCOXANTHINSfucoxanthins n. Plural of fucoxanthin.
FUCOXANTHIN n. a brown carotenoid pigment occurring esp. in the chloroplasts of brown algae.
FUNCTIONALLYfunctionally adv. In a functional manner.
FUNCTIONAL adv. serving a function.
FUNCTIONATEDfunctionated v. Simple past tense and past participle of functionate.
FUNCTIONATE v. to perform a function.
FUNCTIONATESfunctionates v. Third-person singular simple present indicative form of functionate.
FUNCTIONATE v. to perform a function.
MALFUNCTIONSmalfunctions n. Plural of malfunction.
malfunctions v. Third-person singular simple present indicative form of malfunction.
MALFUNCTION v. to function imperfectly or badly.
NONFACULTIESNONFACULTY n. a position that is not part of an academic faculty.
UNCONFINABLEunconfinable adj. That cannot be confined.
UNCONFINABLE adj. not confinable.
UNIFICATIONSunifications n. Plural of unification.
UNIFICATION n. the act of unifying.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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