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There are 4 twelve-letter words containing A, 2C, L, O, S and Z

CATHOLICIZEScatholicizes v. Third-person singular simple present indicative form of catholicize.
Catholicizes v. Third-person singular simple present indicative form of Catholicize.
CATHOLICIZE v. to make catholic, also CATHOLICISE.
CYCLAZOCINEScyclazocines n. Plural of cyclazocine.
CYCLAZOCINE n. a synthetic drug protecting against the addictive effects of the morphine group.
CYCLIZATIONScyclizations n. Plural of cyclization.
CYCLIZATION n. the formation of a ring in a chemical compound, also CYCLISATION.
ESCHSCHOLZIAeschscholzia n. Any of the flowers in the Eschscholzia genus, especially the California poppy (Eschscholzia californica).
Eschscholzia prop.n. A taxonomic genus within the family Papaveraceae – The California poppy and similar plants.
ESCHSCHOLZIA n. a flower of the poppy family, also ESCHSCHOLTZIA.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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