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There are 4 twelve-letter words containing 2A, F, N, O, P and S

PROFANATIONSprofanations n. Plural of profanation.
PROFANATION n. the act or an instance of profaning.
PUFFTALOONASPUFFTALOONAS n. (Australian) a type of fried cake, eaten hot with jam, honey or sugar, also PUFTALOON, PUFTALOONIES.
SAPONIFIABLEsaponifiable adj. Suitable for use in soap production.
saponifiable adj. (Organic chemistry, of a lipid) That can be saponified.
SAPONIFIABLE adj. capable of being converted into soap.
SULFORAPHANEsulforaphane n. (Organic chemistry, medicine) An antimicrobial compound, 1-isothiocyanato-4-methylsulfinylbutane, that…

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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