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There are 18 twelve-letter words containing 2A, D, E, I, M and P

ALDERMANSHIPaldermanship n. The condition, position, or office of an alderman.
ALDERMANSHIP n. the office of alderman.
AMPHIDENTATEAMPHIDENTATE adj. of a ligand, able to coordinate through either of two different atoms, also AMBIDENTATE.
APPROXIMATEDapproximated v. Simple past tense and past participle of approximate.
approximated adj. Calculated by approximation.
APPROXIMATE v. to come close to.
COMPAGINATEDcompaginated v. Simple past tense and past participle of compaginate.
COMPAGINATE v. to join; to connect.
DERMAPLANINGdermaplaning n. The exfoliation of the skin by means of a scalpel.
DERMAPLANING n. a cosmetic treatment, often used to treat acne scars, in which surface irregularities are surgically scraped to give the skin a smoother appearance.
EMPARADISINGemparadising v. Present participle of emparadise.
EMPARADISE v. (Milton) to put in a state like paradise; to make supremely happy.
MADREPORIANSmadreporians n. Plural of madreporian.
MADREPORIAN n. a coral, a madrepore.
MANSPREADINGmanspreading n. (Informal, derogatory) The practice of men splaying their legs open wide when sitting on public transport…
manspreading v. Present participle of manspread.
MANSPREADING n. the practice by a male passenger on public transport of sitting with his legs wide apart, so denying space to passengers beside him.
PACHYDERMIASPACHYDERMIA n. elephantiasis.
PAEDOBAPTISMpaedobaptism n. The baptism of infants or young children.
pædobaptism n. Obsolete spelling of paedobaptism.
PAEDOBAPTISM n. the doctrine of infant baptism.
PANDAEMONIUMpandaemonium n. Alternative spelling of pandemonium.
pandæmonium n. (Archaic) Alternative form of pandemonium.
Pandæmonium prop.n. The high capital of Hell in John Milton’s Paradise Lost.
PANDEMONIANSPANDEMONIAN n. a noisy and disorderly person.
PARAMEDICALSparamedicals n. Plural of paramedical.
PARAMEDICAL n. a paramedical worker, also PARAMEDIC, PARAMEDICO.
PARAMETRISEDparametrised v. Simple past tense and past participle of parametrise.
PARAMETRISE v. to express in terms of parameters, also PARAMETRIZE.
PARAMETRIZEDparametrized v. Simple past tense and past participle of parametrize.
parametrized adj. Furnished with, or described in terms of parameters.
PARAMETRIZE v. to express in terms of parameters, also PARAMETRISE.
PTERIDOMANIApteridomania n. A craze, in 19th-century England, for collecting ferns and for using images of ferns in the decorative arts.
PTERIDOMANIA n. a passion for ferns.
SEMIPALMATEDsemipalmated adj. Having webs between some, but not all, of the toes.
SEMIPALMATED adj. having the toes joined only part way down with a web, also SEMIPALMATE.
TRYPARSAMIDEtryparsamide n. A particular antiinfective drug.
TRYPARSAMIDE n. a synthetic crystalline compound of arsenic used in the treatment of trypanosomal and other protozoan infections.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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