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There are 4 twelve-letter words containing 2A, C, 2M and 2T

ASYMPTOMATICasymptomatic adj. (Pathology) Not exhibiting any symptoms of disease, as for example in subclinical cases.
asymptomatic n. A patient who exhibits no symptoms of disease.
ASYMPTOMATIC adj. having, displaying or producing no symptoms.
COMMENTARIATcommentariat n. (Informal) All the pundits and commentators of the news media collectively.
COMMENTARIAT n. the group of people who provide opinion and analysis of events in the news.
MATHEMATICALmathematical adj. Of, or relating to mathematics.
mathematical adj. (Figuratively) Extremely precise and accurate, as though having the exactness of a mathematical equation.
mathematical adj. Possible but highly improbable.
TRIGRAMMATICtrigrammatic adj. Containing three letters or characters, or three sets of letters or characters.
TRIGRAMMATIC adj. relating to a trigram, also TRIGRAMMIC.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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