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There are 18 twelve-letter words containing 2A, C, 2M, S and T

ACCOMMODATESaccommodates v. Third-person singular simple present indicative form of accommodate.
ACCOMMODATE v. to make fit, suitable, or congruous.
ACHROMATISMSachromatisms n. Plural of achromatism.
ACHROMATISM n. the state of being achromatic.
AMERCIAMENTSamerciaments n. Plural of amerciament.
AMERCIAMENT n. the infliction of a fine, also AMERCEMENT.
ASYMMETRICALasymmetrical adj. Not symmetrical.
asymmetrical adj. (Of a question) Presenting a false dilemma, or a choice between two things which are not opposites.
ASYMMETRICAL adj. not symmetrical, also ASYMMETRIC.
ASYMPTOMATICasymptomatic adj. (Pathology) Not exhibiting any symptoms of disease, as for example in subclinical cases.
asymptomatic n. A patient who exhibits no symptoms of disease.
ASYMPTOMATIC adj. having, displaying or producing no symptoms.
COCKAMAMIESTCOCKAMAMY adj. ridiculous, incredible, also COCKAMAMIE.
COMMISSARIATcommissariat n. A supply of food.
commissariat n. The department of an army that supplies provisions for the troops.
commissariat n. (Historical) A department of the government of the Soviet Union in the early period of its existence.
CRASSAMENTUMcrassamentum n. (Obsolete) The solid component of blood, blood from which serum has been removed; a mass of coagulated…
CRASSAMENTUM n. (Latin) a clot of blood.
DRAMATICISMSdramaticisms n. Plural of dramaticism.
DRAMATICISM n. the quality of being dramatic.
GRAMMATICISEgrammaticise v. Non-Oxford standard spelling of grammaticize.
GRAMMATICISE v. to make grammatical, also GRAMMATICIZE.
GRAMMATICISMgrammaticism n. (Dated) A point or principle of grammar.
GRAMMATICISM n. a point of grammar.
MACROGAMETESmacrogametes n. Plural of macrogamete.
MACROGAMETE n. the larger and usually female gamete of a heterogamous organism, also MEGAGAMETE.
MARCATISSIMOmarcatissimo adv. (Music) Extremely marcato.
MARCATISSIMO adv. in a very marcato manner.
MATCHMAKINGSmatchmakings n. Plural of matchmaking.
match-makings n. Plural of match-making.
MATCHMAKING n. the business of bringing suitable people together for marriage.
MYCOPLASMATAmycoplasmata n. Plural of mycoplasma.
MYCOPLASMA n. a member of the Mycoplasma, a variety of pathogenic agents apparently neither viruses not true bacteria.
MYTHOMANIACSmythomaniacs n. Plural of mythomaniac.
MYTHOMANIAC n. a sufferer from mythomania, an excessive or abnormal propensity for lying and exaggerating.
PRAGMATICISMpragmaticism n. A Peircean philosophy based on strict logic, the immutability of truth, the reality of infinity, and…
PRAGMATICISM n. the philosophic doctrine of C. S. Peirce.
SARCOLEMMATAsarcolemmata n. Plural of sarcolemma.
SARCOLEMMA n. the cell membrane enclosing a muscle fibre.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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