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There are 17 twelve-letter words containing 2A, C, 2M, O and S

ACCOMMODATESaccommodates v. Third-person singular simple present indicative form of accommodate.
ACCOMMODATE v. to make fit, suitable, or congruous.
ACHROMATISMSachromatisms n. Plural of achromatism.
ACHROMATISM n. the state of being achromatic.
ASYMPTOMATICasymptomatic adj. (Pathology) Not exhibiting any symptoms of disease, as for example in subclinical cases.
asymptomatic n. A patient who exhibits no symptoms of disease.
ASYMPTOMATIC adj. having, displaying or producing no symptoms.
CHASMOGAMIESCHASMOGAMY n. the opening of a flower in order to be fertilized.
CHASMOGAMOUSchasmogamous adj. Exhibiting chasmogamy.
CHASMOGAMOUS adj. relating to chasmogamy, the opening of a flower in order to be fertilized, also CHASMOGAMIC.
COCKAMAMIESTCOCKAMAMY adj. ridiculous, incredible, also COCKAMAMIE.
COMMISSARIALcommissarial adj. Of or pertaining to a commissary.
COMMISSARIAL adj. of or like a commissar.
COMMISSARIATcommissariat n. A supply of food.
commissariat n. The department of an army that supplies provisions for the troops.
commissariat n. (Historical) A department of the government of the Soviet Union in the early period of its existence.
HAEMACHROMESHAEMACHROME n. a blood pigment, such as haemoglobin, that carries oxygen, also HEMACHROME.
MACROGAMETESmacrogametes n. Plural of macrogamete.
MACROGAMETE n. the larger and usually female gamete of a heterogamous organism, also MEGAGAMETE.
MARCATISSIMOmarcatissimo adv. (Music) Extremely marcato.
MARCATISSIMO adv. in a very marcato manner.
MARCONIGRAMSmarconigrams n. Plural of marconigram.
MARCONIGRAM n. a message sent by wireless telegraphy.
MESOAMERICANmesoamerican adj. Alternative form of Mesoamerican.
Mesoamerican adj. Of or pertaining to Mesoamerica.
Mesoamerican n. A native or inhabitant of Mesoamerica.
MICROMANAGESmicromanages v. Third-person singular simple present indicative form of micromanage.
MICROMANAGE v. to manage at a detailed level.
MYCOPLASMATAmycoplasmata n. Plural of mycoplasma.
MYCOPLASMA n. a member of the Mycoplasma, a variety of pathogenic agents apparently neither viruses not true bacteria.
MYTHOMANIACSmythomaniacs n. Plural of mythomaniac.
MYTHOMANIAC n. a sufferer from mythomania, an excessive or abnormal propensity for lying and exaggerating.
SARCOLEMMATAsarcolemmata n. Plural of sarcolemma.
SARCOLEMMA n. the cell membrane enclosing a muscle fibre.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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