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There are 15 twelve-letter words containing 2A, C, L, 2M and T

AGRAMMATICALagrammatical adj. (Grammar) Not grammatical; ungrammatical.
AGRAMMATICAL adj. not grammatical.
ASYMMETRICALasymmetrical adj. Not symmetrical.
asymmetrical adj. (Of a question) Presenting a false dilemma, or a choice between two things which are not opposites.
ASYMMETRICAL adj. not symmetrical, also ASYMMETRIC.
CALCEAMENTUMcalceamentum n. (Historical) A red silk embroidered sandal forming part of the insignia of the Holy Roman Empire.
CALCEAMENTUM n. (Latin) a red silk embroidered sandal forming part of the insignia of the Holy Roman Empire.
COMMENTARIALcommentarial adj. Relating to a commentary.
COMMENTARIAL adj. of or like a commentary.
EMBLEMATICALemblematical adj. Emblematic.
EMBLEMATICAL adj. of, relating to, or constituting an emblem, also EMBLEMATIC.
IMMACULATELYimmaculately adv. In an immaculate manner; in a manner free of stain or blemish; without being defiled.
immaculately adv. In a manner free of error; in a perfect or flawless manner.
IMMACULATE adv. having no stain or blemish.
MACROCLIMATEmacroclimate n. The climate of a relatively large geographic area.
MACROCLIMATE n. large-scale climate.
MANOMETRICALmanometrical adj. Alternative form of manometric.
MANOMETRICAL adj. relating to manometry, the measurement of the pressure of fluids, also MANOMETRIC.
MATHEMATICALmathematical adj. Of, or relating to mathematics.
mathematical adj. (Figuratively) Extremely precise and accurate, as though having the exactness of a mathematical equation.
mathematical adj. Possible but highly improbable.
MEDICAMENTALmedicamental adj. (Archaic) Of or pertaining to medicaments or healing applications; having the qualities of medicaments.
MEDICAMENTAL adj. relating to medicaments, also MEDICAMENTARY.
MELODRAMATICmelodramatic adj. Of or pertaining to melodrama; like or suitable to a melodrama; unnatural in situation or action.
melodramatic adj. Exaggeratedly emotional or sentimental.
melo-dramatic adj. Alternative form of melodramatic.
MONOTHALAMICmonothalamic adj. (Botany) monothalamous.
MONOTHALAMIC adj. of fruit, formed from a single flower.
MYCOPLASMATAmycoplasmata n. Plural of mycoplasma.
MYCOPLASMA n. a member of the Mycoplasma, a variety of pathogenic agents apparently neither viruses not true bacteria.
PANTOMIMICALpantomimical adj. (Now rare) Expressed or carried out using mime or mimicry.
pantomimical adj. (Now rare) Like or pertaining to a pantomime.
PANTOMIMICAL adj. like a pantomime, also PANTOMIMIC.
SARCOLEMMATAsarcolemmata n. Plural of sarcolemma.
SARCOLEMMA n. the cell membrane enclosing a muscle fibre.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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