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There are 15 twelve-letter words containing 2A, C, F, I and 2R

AIRCRAFTSMANaircraftsman n. An aircraftman.
AIRCRAFTSMAN n. a member of the lowest (male) rank in the RAF, also AIRCRAFTMAN.
AIRCRAFTSMENaircraftsmen n. Plural of aircraftsman.
AIRCRAFTSMAN n. a member of the lowest (male) rank in the RAF, also AIRCRAFTMAN.
ANTIAIRCRAFTantiaircraft adj. Alternative spelling of anti-aircraft.
antiaircraft n. Alternative spelling of anti-aircraft.
anti-aircraft adj. (Military) Intended to attack aircraft.
FIBROSARCOMAfibrosarcoma n. (Oncology) A fibroblastic sarcoma: a malignant tumor derived from fibrous connective tissue.
FIBROSARCOMA n. a sarcoma formed of spindle-shaped cells in collagenous fibrils.
FORECARRIAGEforecarriage n. The forward part of the running gear of a four-wheeled carriage.
FORECARRIAGE n. the front part of a carriage, with an arrangement for independent movement of the fore-wheels.
FRACTIONATORfractionator n. (Chemistry) A piece of chemical engineering or laboratory apparatus that is used to separate the components…
FRACTIONATOR n. a plant for carrying out fractional distillation.
FRACTOSTRATIFRACTOSTRATUS n. a type of cloud.
HANDICRAFTERhandicrafter n. One who engages in handicrafts.
HANDICRAFTER n. one who practises handicrafts.
MICROFILARIAmicrofilaria n. (Biology) The very small larva of a filarial worm.
MICROFILARIA n. the minute larval form of a filarial worm.
PREFABRICATEprefabricate v. (Transitive) To manufacture (A building, etc.) in standard components that can be fitted together on site.
PREFABRICATE v. to make standardized parts of beforehand, for assembling later.
RAREFACTIONSrarefactions n. Plural of rarefaction.
RAREFACTION n. the act of rarefying.
RAREFICATIONrarefication n. Rarefaction.
RAREFICATION n. the act of rarefying.
REFRACTARIESREFRACTARY n. a substance that is able to resist high temperatures, etc., used in lining furnaces, etc.
SCARIFICATORscarificator n. (Surgery, archaic) An instrument, principally used in cupping, containing several lancets that are moved…
SCARIFICATOR n. a surgical instrument for scarifying, also SCARIFIER.
TRAFFICATORStrafficators n. Plural of trafficator.
TRAFFICATOR n. formerly, a movable pointer raised or lowered by the driver of a vehicle to warn of a change of direction.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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