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There are 6 twelve-letter words containing 2A, C, F, I and 2O

AFFICIONADOSafficionados n. Plural of afficionado.
AFFICIONADO n. (Spanish) a devotee, admirer, an enthusiastic fan, also AFICIONADO.
FIBROSARCOMAfibrosarcoma n. (Oncology) A fibroblastic sarcoma: a malignant tumor derived from fibrous connective tissue.
FIBROSARCOMA n. a sarcoma formed of spindle-shaped cells in collagenous fibrils.
FOCALISATIONfocalisation n. Alternative form of focalization.
FOCALISATION n. the act of focalising, also FOCALIZATION.
FOCALIZATIONfocalization n. (Literature) The perspective through which a narrative is presented.
focalization n. (Optics) Putting into focus.
FOCALIZATION n. the act of focalizing, also FOCALISATION.
FRACTIONATORfractionator n. (Chemistry) A piece of chemical engineering or laboratory apparatus that is used to separate the components…
FRACTIONATOR n. a plant for carrying out fractional distillation.
FRANCOPHOBIAFrancophobia n. The hatred or fear of France, its people and culture.
Francophobia n. The hatred or fear of the presence of the French language and its native speakers.
FRANCOPHOBIA n. fear of France or the French.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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