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There are 4 twelve-letter words containing 2A, C, D and 3E

ACETALDEHYDEacetaldehyde n. (Organic chemistry) An organic compound, (CH3CHO). Sometimes called ethanal or acetic aldehyde. See…
ACETALDEHYDE n. a chemical compound.
DECAFFEINATEdecaffeinate v. (Transitive) To remove the caffeine from something (especially from coffee).
DECAFFEINATE v. to remove caffeine from.
HEADTEACHERSheadteachers n. Plural of headteacher.
head␣teachers n. Plural of head teacher.
HEADTEACHER n. a teacher in charge of a school.
HENDECAHEDRAhendecahedra n. Plural of hendecahedron.
HENDECAHEDRON n. a solid figure having 11 plane faces.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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