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There are 3 twelve-letter words containing 3A, C, N and 2O

ANGIOSARCOMAangiosarcoma n. (Oncology) Any malignant tumour of vascular tissue.
ANGIOSARCOMA n. a malignant tumour of the vascular epithelia, occurring e.g. in the liver.
COADAPTATIONcoadaptation n. Alternative spelling of co-adaptation.
co-adaptation n. A mutual adaptation of species, organs or genes.
COADAPTATION n. the state of being mutually adapted.
MONOMANIACALmonomaniacal adj. Fanatical, or obsessed with one cause or idea to the exclusion of other concerns.
monomaniacal adj. Of or relating to a monomaniac.
MONOMANIACAL adj. obsessed with one subject only.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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