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There are 12 twelve-letter words containing 3A, C, 2I and S

ACADEMICIANSacademicians n. Plural of academician.
Academicians n. Plural of Academician.
ACADEMICIAN n. a member of an academy.
ANABAPTISTICAnabaptistic adj. Of or relating to the Anabaptists.
ANABAPTISTIC adj. relating to anabaptism.
ANASTIGMATICanastigmatic adj. (Of the eye, or a lens system) Free from astigmatism.
ANASTIGMATIC adj. free from astigmatism.
BACILLAEMIASBACILLAEMIA n. the presence of bacilli in the blood, also BACILLEMIA.
CABALISTICALcabalistical adj. (Now rare) Cabalistic.
CABALISTICAL adj. relating to the cabbala.
CANALISATIONcanalisation n. The conversion of a river or other waterway to a canal.
canalisation n. The management of something using defined channels of communication.
canalisation n. (Genetics) The ability of a genotype to produce the same phenotype regardless of variability of its environment.
MACADAMISINGmacadamising v. Present participle of macadamise.
MACADAMISE v. to cover a road with small broken stones, also MACADAMIZE.
MARCASITICALmarcasitical adj. Alternative form of marcasitic.
MARCASITICAL adj. of or like marcasite.
PARADISAICALparadisaical adj. Of or relating to paradise (or heaven).
PARADISAICAL adj. of or like paradise, also PARADISAIC, PARADISEAN, PARADISIAC, PARADISIACAL, PARADISIAL, PARADISIAN, PARADISICAL.
PARADISIACALparadisiacal adj. Of or resembling paradise.
PARADISIACAL adj. of or like paradise, also PARADISAIC, PARADISAICAL, PARADISEAN, PARADISIAC, PARADISIAL, PARADISIAN, PARADISICAL.
PARAPHILIACSparaphiliacs n. Plural of paraphiliac.
PARAPHILIAC n. a person who indulges in paraphilia, abnormal sexual practices.
TALISMANICALtalismanical adj. Alternative form of talismanic.
TALISMANICAL adj. of or like a talisman, also TALISMANIC.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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