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There are 5 twelve-letter words containing 4A, E, I and S

ANAPAESTICALanapaestical adj. Anapestic.
ANAPAESTICAL adj. in the form of an anapaest, two short metrical syllables followed by one long one.
ASPARAGINASEasparaginase n. (Biochemistry) An enzyme that catalyzes the hydrolysis of asparagine to aspartic acid, used in chemotherapy.
ASPARAGINASE n. an enzyme that causes asparagine to hydrolyse to aspartic acid and ammonia.
CARAVANSERAIcaravanserai n. A roadside inn having a central courtyard where caravans can rest.
caravanserai n. (Humorous) An upscale hotel.
caravanserai n. A home or shelter for caravans.
PARASITAEMIAparasitaemia n. Alternative spelling of parasitemia.
PARASITAEMIA n. the presence of parasites in the blood.
THALASSAEMIAthalassaemia n. Alternative spelling of thalassemia.
THALASSAEMIA n. anemia resulting from faulty synthesis of hemoglobin, also THALASSEMIA.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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