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There are 7 ten-letter words containing 2A, O, P, 2T and U

AMPUTATIONamputation n. Surgical removal of all or part of a limb, etc.
amputation n. The loss of a limb, etc. through trauma.
AMPUTATION n. the act of amputating.
AMPUTATORSamputators n. Plural of amputator.
AMPUTATOR n. one who amputates.
AUTOPISTASautopistas n. Plural of autopista.
AUTOPISTA n. (Spanish) a motorway.
AUTOPLASTYautoplasty n. (Medicine, surgery, dated) The process of artificially repairing lesions by taking a piece of healthy…
AUTOPLASTY n. grafting tissue from patient's own body.
AUTOPTICALautoptical adj. Alternative form of autoptic.
AUTOPTICAL adj. based on personal observation, as autoptic testimony, also AUTOPTIC.
NATUROPATHnaturopath n. (Alternative medicine) A practitioner of naturopathy, a nature healer.
NATUROPATH n. a person who practises naturopathy.
PORTMANTUAportmantua n. Obsolete form of portmanteau (“case”).
PORTMANTUA n. (obsolete) a portmanteau, also PORTMANTEAU, PORTMANTLE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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