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There are 7 ten-letter words containing 2A, I, 2O, P and T

APOTROPAICapotropaic adj. (Religion, mysticism) Intended to ward off evil.
apotropaic n. An agent intended to ward off evil.
APOTROPAIC adj. averting or combating evil.
AUTOPHOBIAautophobia n. The morbid fear of being alone or of oneself.
autophobia n. Self-hatred.
autophobia n. Fear or dislike of automobiles.
CACOTOPIANCACOTOPIAN adj. of or like a cacotopia, a state in which everything is as bad as it can be.
CACOTOPIAScacotopias n. Plural of cacotopia.
CACOTOPIA n. a state in which everything is as bad as it can be.
COAPTATIONcoaptation n. The bringing together of two parts to form an approximated positioning; used especially of a dislocated…
COAPTATION n. joining or fitting together.
PROTANOPIAprotanopia n. (Pathology) A form of color blindness. Involves a defect in distinguishing between red and green.
PROTANOPIA n. colour-blindness with respect to red.
TOPAGNOSIATOPAGNOSIA n. a symptom of disease of or damage to the brain in which a person cannot identify a part of the body that has been touched, also TOPAGNOSIS.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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