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There are 3 ten-letter words containing 2A, E, N, O, P and U

ANDROPAUSEandropause n. The male equivalent of the menopause in women; characterised by a decline in libido and overall energy.
ANDROPAUSE n. the male menopause.
CANTALOUPEcantaloupe n. A melon of species Cucumis melo subsp. melo with sweet orange flesh, with numerous cultivars in several…
cantaloupe n. An orange colour, like that of cantaloupe flesh.
CANTALOUPE n. (Italian) a small musk melon with a ribbed skin, also CANTALOUP.
MENOPAUSALmenopausal adj. Of, or pertaining to the menopause.
MENOPAUSAL adj. relating to the menopause, also MENOPAUSIC.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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