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There are 18 ten-letter words containing 2A, C, E and 3S

ASCARIASESascariases n. Plural of ascariasis.
ASCARIASIS n. infestation with, or disease caused by, ascarids.
ASSISTANCEassistance n. Aid; help; the act or result of assisting.
ASSISTANCE n. the act of assisting or the help supplied.
ASSOCIATESassociates n. Plural of associate.
associates v. Third-person singular simple present indicative form of associate.
Associates n. Plural of Associate.
ASSONANCESassonances n. Plural of assonance.
ASSONANCE n. vowel-rhyme, coincidence of vowel sound without regard to consonants.
ASSURANCESassurances n. Plural of assurance.
ASSURANCE n. confidence, a feeling of certainty, also SURANCE.
CAESARISMSCaesarisms n. Plural of Caesarism.
CAESARISM n. imperialism.
CANVASSERScanvassers n. Plural of canvasser.
CANVASSER n. one who goes from door to door raising votes, also CANVASER.
CASSAREEPScassareeps n. Plural of cassareep.
CASSAREEP n. (Tupi) the juice of the cassava root, made into syrup and used in sauces.
CASSONADEScassonades n. Plural of cassonade.
CASSONADE n. (French) unrefined cane-sugar (imported in casks).
CASUALISEScasualises v. Third-person singular simple present indicative form of casualise.
CASUALISE v. to turn (regular workers) into casual workers, also CASUALIZE.
CASUALNESScasualness n. The state of being casual.
casualness n. A relaxed and nonchalant attitude.
CASUALNESS n. the state of being casual.
CATASTASEScatastases n. Plural of catastasis.
CATASTASIS n. the part of drama where action is at its height.
CLASSMATESclassmates n. Plural of classmate.
CLASSMATE n. one in the same class.
MASSACRERSmassacrers n. Plural of massacrer.
MASSACRER n. one who massacres.
NAISSANCESNAISSANCE n. (French) birth.
SACRALISESsacralises v. Third-person singular simple present indicative form of sacralise.
SACRALISE v. to make sacred, also SACRALIZE.
SMEARCASESSMEARCASE n. (German) cottage cheese, also SMIERCASE.
STAIRCASESstaircases n. Plural of staircase.
STAIRCASE n. a flight of stairs, its supporting framework, and, usually, a handrail or banisters.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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