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There are 7 ten-letter words containing 2A, 2C, E and 2N

ANTICANCERanticancer adj. (Medicine) That is used to treat cancer.
anti-cancer adj. Alternative form of anticancer.
ANTICANCER adj. of a drug, designed to prevent cancer.
ASCENDANCEascendance n. Ascendancy, superiority; the act of ascending.
ASCENDANCE n. the state of being ascendant, also ASCENDANCY, ASCENDENCE, ASCENDENCY.
ASCENDANCYascendancy n. Supremacy; dominant control; the quality of being in the ascendant.
ascendancy n. (Historical, Ireland, sometimes capitalized) A class of Protestant landowners and professionals that…
ascendancy n. (Ecology) A quantitative attribute of an ecosystem, defined as a function of the ecosystem’s trophic…
CACHINNATEcachinnate v. (Intransitive) To laugh loudly, immoderately, or too often.
CACHINNATE v. to laugh loudly or immoderately.
CANONICATEcanonicate n. The office of a canon; a canonry.
CANONICATE n. the rank or office of a canon.
CATANANCHECATANANCHE n. any plant of the South European genus Catananche, some of which are grown for their blue and white flowers.
WANCHANCIEWANCHANCIE adj. (Scots) unlucky, dangerous, uncanny, also WANCHANCY.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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