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There are 19 words containing 2A, D, E, M and X

MALAXEDmalaxed v. Simple past tense and past participle of malax.
MALAX v. to soften by kneading, also MALAXATE.
MALAXATEDmalaxated v. Simple past tense and past participle of malaxate.
MALAXATE v. to soften by kneading, also MALAX.
TAXIDERMALtaxidermal adj. Of, or pertaining to, taxidermy.
TAXIDERMAL adj. relating to taxidermy, also TAXIDERMIC.
AXIOMATISEDaxiomatised v. Simple past tense and past participle of axiomatise.
AXIOMATISE v. to make axiomatic, also AXIOMATIZE.
AXIOMATIZEDaxiomatized v. Simple past tense and past participle of axiomatize.
AXIOMATIZE v. to reduce to a system of axioms, also AXIOMATISE.
HEXADECIMALhexadecimal n. (Arithmetic, computing, uncountable) A number system with base sixteen, using the digits 0, 1, 2, 3…
hexadecimal n. (Countable, computing) A number expressed in the hexadecimal system.
hexadecimal adj. Of a number, expressed in hexadecimal.
APPROXIMATEDapproximated v. Simple past tense and past participle of approximate.
approximated adj. Calculated by approximation.
APPROXIMATE v. to come close to.
EXTRAMUNDANEextramundane adj. Beyond mundane, beyond ordinary.
extramundane adj. Extraterrestrial; occurring or originating outside of the Earth.
EXTRAMUNDANE adj. beyond the known universe.
HEXADECIMALShexadecimals n. Plural of hexadecimal.
HEXADECIMAL n. a number system with a base of 16.
HEXAGRAMMOIDHEXAGRAMMOID n. a hexagram shape.
DEXAMETHASONEdexamethasone n. (Pharmacology, biochemistry) A synthetic member of the glucocorticoid-class of steroid hormones, having…
DEXAMETHASONE n. a synthetic glucocorticoid used esp. as an anti-inflammatory agent.
HEXAGRAMMOIDSHEXAGRAMMOID n. a hexagram shape.
MAXILLIPEDARYmaxillipedary adj. Of, or pertaining to, the maxilliped.
MAXILLIPEDARY adj. like a maxilliped, one of the mouth appendages of Crustacea.
DEXAMETHASONESdexamethasones n. Plural of dexamethasone.
DEXAMETHASONE n. a synthetic glucocorticoid used esp. as an anti-inflammatory agent.
DEXAMPHETAMINEdexamphetamine n. Dextroamphetamine.
DEXAMPHETAMINE n. the dextrorotatory isomer of amphetamine, used as a stimulant.
EXTRAPYRAMIDALextrapyramidal adj. Of or pertaining to the neural pathways that are independent of the pyramidal tract.
EXTRAPYRAMIDAL adj. situated outside of the pyramidal tracts.
HEXOSAMINIDASEhexosaminidase n. (Biochemistry) Any enzyme that catalyzes the hydrolysis of terminal hexosamine residues in hexosaminides.
HEXOSAMINIDASE n. either of two hydrolytic enzymes that catalyze the splitting off of a hexose from a ganglioside and are deficient in some metabolic diseases.
DEXAMPHETAMINESDEXAMPHETAMINE n. the dextrorotatory isomer of amphetamine, used as a stimulant.
HEXOSAMINIDASEShexosaminidases n. Plural of hexosaminidase.
HEXOSAMINIDASE n. either of two hydrolytic enzymes that catalyze the splitting off of a hexose from a ganglioside and are deficient in some metabolic diseases.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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