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There are 19 words containing 2A, 2D, F and T

FATHEADEDfatheaded adj. Characteristic of a fathead; stupid.
FATHEADED adj. stupid.
DEFAECATEDdefaecated v. Simple past tense and past participle of defaecate.
defæcated v. Obsolete spelling of defecated; simple past tense and past participle of defæcate.
DEFAECATE v. to void excrement, also DEFECATE.
DEFALCATEDdefalcated v. Simple past tense and past participle of defalcate.
DEFALCATE v. to embezzle money held on trust.
HANDFASTEDhandfasted v. Simple past tense and past participle of handfast.
HANDFAST v. to betroth.
DEFLAGRATEDdeflagrated v. Simple past tense and past participle of deflagrate.
DEFLAGRATE v. to burn suddenly, generally with flame and crackling noise.
FATHEADEDLYfatheadedly adv. Stupidly.
FATHEADED adv. stupid.
HANDCRAFTEDhandcrafted adj. Made by hand or using the hands, as opposed to by mass production or using machinery.
HANDCRAFT v. to fashion by hand.
ANTIDANDRUFFantidandruff adj. Countering or preventing dandruff.
ANTIDANDRUFF adj. designed to cure dandruff.
DEFRAUDATIONdefraudation n. (Obsolete) The act of defrauding; a taking by fraud.
DEFRAUDATION n. the act of defrauding.
DANDIFICATIONdandification n. The condition or state of a man who is overly concerned about his clothes and appearance.
DANDIFICATION n. the act of dandifying.
DECAFFEINATEDdecaffeinated adj. From which caffeine has been removed (e.g. decaffeinated coffee).
DECAFFEINATE v. to remove caffeine from.
DEFRAUDATIONSdefraudations n. Plural of defraudation.
DEFRAUDATION n. the act of defrauding.
DISAFFILIATEDdisaffiliated v. Simple past tense and past participle of disaffiliate.
DISAFFILIATE v. to end an affiliation.
FATHEADEDNESSfatheadedness n. The quality of being fatheaded.
FATHEADED n. stupid.
FEATHERHEADEDfeatherheaded adj. Alternative form of feather-headed.
feather-headed adj. (Colloquial) giddy; frivolous; foolish.
FEATHERHEADED adj. foolish, empty-headed.
GRANDFATHEREDgrandfathered v. Simple past tense and past participle of grandfather.
GRANDFATHER v. to exempt (an activity, person, etc.) from a new piece of legislation, restriction or the like.
DANDIFICATIONSdandifications n. Plural of dandification.
DANDIFICATION n. the act of dandifying.
DEACIDIFICATIONdeacidification n. (Chemistry) The act or process of removing or neutralizing acid.
DEACIDIFICATION n. the act of deacidifying.
FATHEADEDNESSESFATHEADEDNESS n. FATHEADED, stupid.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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