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There are 3 eight-letter words containing A, C, I, M and 2U

ACICULUMaciculum n. (Botany, zoology) A needlelike spine or bristle, specially the seta of an annelid.
ACICULUM n. (Latin) a bristlelike part.
GUAIACUMguaiacum n. Any of a number of species of tree of the genus Guaiacum, native to the West Indies and parts of the Americas.
guaiacum n. The wood or resin of this tree.
GUAIACUM n. a medicinal resin, also GUAIAC, GUAIOCUM.
GUAIOCUMGUAIOCUM n. a medicinal resin, also GUAIACUM, GUAIAC.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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