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There are 5 eight-letter words containing 2A, I, N, T and X

ANATEXISanatexis n. (Geology) The metamorphism of plutonic rock into magma in the lower levels of the crust.
ANATEXIS n. the partial melting of rocks, esp. in the formation of metamorphic rocks.
ANATOXINanatoxin n. A bacterial toxin (usually an exotoxin) whose toxicity has been weakened or suppressed.
anatoxin n. A powerful neurotoxin, one of many toxins produced by several species of cyanobacterium.
ANATOXIN n. a potent alkaloid toxin derived from a species of cyanobacteria.
ANTEFIXAantefixa n. (Architecture) Alternative form of antefix.
antefixa n. Plural of antefixum.
ANTEFIXA n. (Latin) an ornament at the end of a classical building, hiding the ends of roof tiles, also ANTEFIX.
LAXATIONlaxation n. The act of loosening or slackening, or the state of being loosened or slackened.
laxation n. Defecation.
LAXATION n. the act of loosening or slackening.
TAXATIONtaxation n. The act of imposing taxes and the fact of being taxed.
taxation n. A particular system of taxing people or companies.
taxation n. The revenue gained from taxes.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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