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There is only one eight-letter word containing 2A, F, M, S and U

FUMARASEfumarase n. An enzyme that in the Krebs cycle acts as a catalyst for the reaction of water and fumarate to form L-malate.
FUMARASE n. an enzyme that catalyses the interconversion of fumaric or malic acid and their salts.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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