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There are 15 eight-letter words containing 2A, C, D, E and M

ACADEMESacademes n. Plural of academe.
ACADEME n. the academic life or world, also ACADEMIA.
ACADEMIAacademia n. (Collective) The scientific and cultural community engaged in higher education and research, taken as a whole.
academia n. Continuous study at higher education institutions; scholarship.
ACADEMIA n. (Greek) the academic life or world, also ACADEME.
ACADEMICacademic adj. Belonging to the school or philosophy of Plato.
academic adj. Belonging to an academy or other higher institution of learning, or a scholarly society or organization.
academic adj. In particular: relating to literary, classical, or artistic studies like the humanities, rather than…
ACELDAMAaceldama n. The potter’s field, said to have lain south of Jerusalem, purchased with the bribe which Judas took…
aceldama n. A field of bloodshed, a place of slaughter.
ACELDAMA n. (Aramaic) a place of bloodshed.
ACETAMIDacetamid n. Obsolete spelling of acetamide.
ACETAMID n. an amide of acetic acid.
ACIDEMIAacidemia n. Alternative form of acidaemia.
ACIDEMIA n. a condition of increased acidity of the blood.
ADAMANCEadamance n. The quality of being adamant.
ADAMANCE n. unyielding hardness, also ADAMANCY.
CAMAILEDcamailed adj. Fitted with a camail.
CAMAILED adj. having a camail.
CAMISADEcamisade n. Alternative form of camisado.
CAMISADE n. (Spanish) an attack made at night, also CAMISADO.
CHAMADESchamades n. Plural of chamade.
CHAMADE n. (historical) a signal made for a parley by beat of a drum.
DECAGRAMdecagram n. (Metrology) An SI unit of mass equal to 101 grams. Symbol: dag.
decagram n. (Geometry) A regular ten-pointed star shape.
DECAGRAM n. a measure equal to ten grams, also DEKAGRAM.
DRACHMAEdrachmae n. Plural of drachma.
DRACHMA n. (Greek) a Greek monetary unit, also DRACHM.
MAENADICmaenadic adj. Of, or pertaining to a maenad; frenzied.
MAENADIC adj. like a maenad, furious, bacchanalian.
MANACLEDmanacled v. Simple past tense and past participle of manacle.
MANACLE v. to handcuff.
MEDACCASMEDACCA n. (Japanese) a small Japanese fish, also MEDAKA.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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