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There are 13 twelve-letter words containing A, E, I, P, U and X

AUXOTROPHIESauxotrophies n. Plural of auxotrophy.
AUXOTROPHY n. the state of being auxotrophic, requiring a specific growth substance beyond the minimum required for normal metabolism.
EXCULPATIONSexculpations n. Plural of exculpation.
EXCULPATION n. the act of exculpating.
EXPUGNATIONSexpugnations n. Plural of expugnation.
EXPUGNATION n. the act of expugning.
EXPURGATIONSexpurgations n. Plural of expurgation.
EXPURGATION n. the act of expurgating.
INEXPUGNABLEinexpugnable adj. Impossible to eliminate or destroy; impregnable.
INEXPUGNABLE adj. not able to be attacked or captured.
INEXPUGNABLYinexpugnably adv. In an inexpugnable manner.
INEXPUGNABLE adv. not able to be attacked or captured.
PANSEXUALISMpansexualism n. (Psychology, historical) The psychological theory that all human activity (mental and physical) is based on sexuality.
pansexualism n. (Rare, chiefly derogatory) Pansexuality.
PANSEXUALISM n. the theory that all thought derives from the sexual instinct.
PANSEXUALISTpansexualist adj. (Psychology) Pertaining to or promoting the psychological theory of pansexualism.
pansexualist n. (Psychology) A proponent of the psychological theory of pansexualism.
pansexualist n. (Rare, sometimes derogatory) A person who is attracted, or who is able to experience attraction, to…
PANSEXUALITYpansexuality n. A sexual orientation characterized by the potential for aesthetic attraction, romantic love and/or sexual…
pansexuality n. (Rare) Sexuality that encompasses all kinds of sexuality.
PANSEXUALITY n. the state of being pansexual.
PARADOXURINEparadoxurine adj. Of, or pertaining to, the genus Paradoxurus.
PARADOXURINE n. any of a number of palm civet species.
SEXTUPLICATEsextuplicate adj. Six times the number, volume, length, etc. (of something else).
sextuplicate adj. Comprising six identical parts.
sextuplicate n. A series, set, collection, or group of six identical copies of something.
SULPHADOXINEsulphadoxine n. Alternative spelling of sulfadoxine.
SULPHADOXINE n. an antibiotic drug of the sulphonamide group, commonly used in combination with pyrimethamine to treat malaria, also SULFADOXINE.
XIPHOPAGUSESXIPHOPAGUS n. a set of Siamese twins joined in the region of the xiphoid cartilage.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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