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There are 18 twelve-letter words containing A, C, F, 2N and U

BIFUNCTIONALbifunctional adj. Having two functions.
bifunctional adj. (Chemistry, of a compound) Having two functional groups or binding sites.
bifunctional adj. (Chemistry, of a reaction) Involving two functional groups or binding sites.
CONFOUNDABLEconfoundable adj. That can be confounded.
CONFOUNDABLE adj. capable of being confounded.
CONFUTATIONSconfutations n. Plural of confutation.
CONFUTATION n. the act of confuting.
DIFUNCTIONALdifunctional adj. Bifunctional.
DIFUNCTIONAL n. a compound with two highly reactive sites in each molecule.
FANCIFULNESSfancifulness n. The quality of being fanciful.
FANCIFULNESS n. the state of being fanciful.
FECUNDATIONSfecundations n. Plural of fecundation.
FECUNDATION n. the act of making fecund.
FUCOXANTHINSfucoxanthins n. Plural of fucoxanthin.
FUCOXANTHIN n. a brown carotenoid pigment occurring esp. in the chloroplasts of brown algae.
FUNCTIONALLYfunctionally adv. In a functional manner.
FUNCTIONAL adv. serving a function.
FUNCTIONATEDfunctionated v. Simple past tense and past participle of functionate.
FUNCTIONATE v. to perform a function.
FUNCTIONATESfunctionates v. Third-person singular simple present indicative form of functionate.
FUNCTIONATE v. to perform a function.
MALFUNCTIONSmalfunctions n. Plural of malfunction.
malfunctions v. Third-person singular simple present indicative form of malfunction.
MALFUNCTION v. to function imperfectly or badly.
NONFACULTIESNONFACULTY n. a position that is not part of an academic faculty.
UNBENEFICIALunbeneficial adj. Not beneficial.
UNBENEFICIAL adj. not beneficial.
UNCONFINABLEunconfinable adj. That cannot be confined.
UNCONFINABLE adj. not confinable.
UNFRANCHISEDunfranchised adj. Not franchised.
UNFRANCHISED adj. not franchised.
UNIFICATIONSunifications n. Plural of unification.
UNIFICATION n. the act of unifying.
UNSANCTIFIEDunsanctified adj. Not having been sanctified; not made sacred; remaining mundane or worldly. #* 1837, L[etitia] E[lizabeth]…
UNSANCTIFIED adj. not sanctified.
UNSANCTIFIESunsanctifies v. Third-person singular simple present indicative form of unsanctify.
UNSANCTIFY v. to remove the sanctity from.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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